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NMP

CAS No. 120-94-5

Other names

N-methylpyrrolidine

N-Methylpyrrolidine (also known as 1-methylpyrrolidine) is a heterocyclic amine and a derivative of pyrrolidine. It has a methyl group (–CH3) attached to the nitrogen atom in the pyrrolidine ring, making it a secondary amine.

  • Package

    200kg/drum

  • Content

Features
  • Solubility:
    Highly soluble in water and a wide range of organic solvents, which makes it suitable for aqueous and organic phase reactions, as well as in formulations requiring both.
    Basicity:
    Can serve as a base in various reactions, such as nucleophilic substitution, deprotonation, and catalysis. It is used as a proton acceptor in several organic synthesis processes.
    Chiral Center:
    The pyrrolidine ring itself introduces chirality to the molecule, which is useful in stereoselective or asymmetric synthesis where specific isomers are required.

Applications
  • Organic Synthesis:

    N-Methylpyrrolidine is used as an intermediate in the synthesis of pharmaceuticals, fine chemicals, and specialty chemicals. It can be involved in reactions like alkylation, oxidation, reduction, and nucleophilic substitution.

  • Solvent in Organic Synthesis:

    Due to its good solvent properties, N-methylpyrrolidine is sometimes used in solvent mixtures for organic reactions, especially those involving basic conditions or reactions requiring amine chemistry.

  • Catalysis:

    It can act as a basic catalyst in various organic reactions, such as amine-catalyzed reactions and Michael additions. It is also employed in heterogeneous catalysis and can act as a co-catalyst in polymerization and oxidative processes.

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